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Image Search Results
Journal: British Journal of Pharmacology
Article Title: Plant sterol enriched functional food and atherosclerosis
doi: 10.1111/bph.13764
Figure Lengend Snippet: Cholesterol and plant sterols are taken up in the enterocyte via NPC1L1. In the enterocyte, cholesterol and plant sterols are differentiated: most cholesterol molecules are esterified and are packed in chylomicrons. Up to 95% of plant sterols are extruded in the intestine via the obligate heterodimers ABCG5/ABCG8. Regulation of the expression of ABCG5/ABCG8 and NPC1L1 affects serum cholesterol and serum plant sterol levels and determines cardiovascular risk. MTP, microsomal transfer protein; ACTA: acyl‐CoA‐cholesterol‐acyltransferase.
Article Snippet: Many renowned international societies such as the European Atherosclerosis Society (EAS) recommend the use of
Techniques: Expressing